Studies on New Steroid Anesthetic CT-1341 (Althesin-Glaxo)
نویسندگان
چکیده
منابع مشابه
clinical studies of ct 1341, a new steroid anesthetic
ct 1314 is a new steroid anesthetic which is used for the rapid induction of anesthesia. its duration of action as well as the time course for the recovery is rapid. it has a high therapeutic index and proved compatible with other drugs used in anesthesiology. no appreciable side effects has been encount e red during anesthesia with thisdrug . to avoid any disturbance in cardio-pulmonary system...
متن کاملThe effect of CT 1341, a new steroid anesthetic, on the isolated heart muscle.
IWATSUKI, N. The Effect of CT 1341, a New Steroid Anesthetic, on the Isolated Heart Muscle. Tohoku J. exp. Med., 1973, 109 (1), 69-75 A direct inotropic effect of CT 1341, a new steroid intravenous anesthetic, upon the myocardium was studied in isolated heart muscles of dogs by measurements of force-velocity relation. CT 1341 at the concentrations over 0.139 ml/100 ml caused a dose-dependent le...
متن کاملEffect of althesin (CT-1341) on thyroid-adrenal function in man.
The effects of althesin on adrenocortical and thyroid function were investigated by measuring plasma concentrations of cortisol, thyroxine (T4) and free thyroxine index (FTI) in 29 surgical patients. Althesin did not change the plasma cortisol concentrations from the preanaesthetic control value; however, the concentrations increased significantly after the start of surgery and thereafter. Alth...
متن کاملThe effect of althesin (CT 1341) on the oxyhaemoglobin dissociation curve in vitro.
Blood from non-smoking donors was incubated with Althesin and the PO2 for half-saturation of haemoglobin at standard pH, PCO2 and temperature (P 50) was measured. The mean P 50 values of blood with blood concentrations of Althesin of 0.14 ml/dl and 0.42 ml/dl were greater (1.14 +/- 0.31 (SEM) mm Hg (P less than 0.005) and 2.22 +/- 0.35 (SEM) mm Hg (P less than 0.001), respectively) than that of...
متن کاملUse of the steroid anaesthetic CT 1341 in birds.
Despite extensive work-on mammals there is a shortage of accurate data on the anaesthesia of birds. Those publications which exist frequently fail to supply information on the methods used to assess the depth of anaesthesia, as was emphasized by Jordan, Sanford and Wright (1960). Birds have a high metabolic rate and a specialized respiratory system and hence frequently react poorly or adversely...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1972
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)31873-6